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Text File | 1991-05-05 | 2.7 KB | 59 lines | [TEXT/MSWD] |
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- SeqSpeak 1.0
- HyperCard DNA Sequence Editor for the Macintosh
- May 4, 1991
-
- Overview of SeqSpeak
-
- SeqSpeak is a simple DNA sequence editor for the Macintosh. Its primary
- purpose is to provide audio feedback during sequence entry while reading an
- autoradiogram. The entry of DNA sequences has been simplified in several
- ways. The keys on the keyboard used to enter sequence have been changed in
- order to minimize hand movement. The mapping between keys and the base
- entered can be set to correspond to the order of the sequencing reactions
- loaded on the gel. SeqSpeak is very useful for entering sequence from paper
- as well. When a key is pressed, the program "speaks" back the base entered
- using digitized sound. The combination of a more convenient keyboard and
- audio feedback enables the user to enter DNA sequence reliably without
- having to look up from the autoradiogram to the computer screen in order to
- be confident that the correct sequence has been entered. Once the sequence
- has been entered, the sequence can be confirmed by having SeqSpeak read
- the sequence aloud while the user follows along the autoradiogram.
-
- SeqSpeak has some additional features which will be useful to some users.
- These include base composition analysis and search/replace functions. More
- importantly, SeqSpeak can save the sequence to a text file on disk which can
- be read by other Macintosh programs. Text files are also a standard way to
- move information between Macs, mainframes and other computers.
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- Setting Up SeqSpeak
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- You need at least a MacPlus running System Version 6.0.5 or later and a copy
- of HyperCard 2.0 (2.0v2 is the latest version as of April 1991) in order to
- use SeqSpeak. Performance is acceptable on a MacPlus, but much better on
- faster Macs. I recommend a minimum of 2 megs RAM if you are running
- HyperCard under Finder and more if you are using HyperCard with
- MultiFinder. HyperCard's default MultiFinder application size is set to
- 1000K. If you are running HyperCard under MultiFinder, increase this to at
- least 1500K. If you are short of RAM, you can make more memory available
- to HyperCard by removing INITs from the System folder and turning off the
- RAM cache. While it may be possible to run SeqSpeak from a floppy disk (I
- haven't tested this), performance will probably be poor. HyperCard reads and
- writes information frequently, so you should copy SeqSpeak and the
- HyperCard application to your hard disk.
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- SeqSpeak may be distributed freely. Let me know what you think about
- SeqSpeak. How could it be improved? I can be reached by mail, phone, or
- e-mail as follows:
-
- Dr. Keith Conover
- Dept. of Biochemistry
- Dalhousie University
- Halifax, Nova Scotia
- Canada B3H 4H7
- (902) 494-3569
- internet: kconover@ac.dal.ca
- Compuserve: 72260,2107 (checked infrequently)
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